The three most widely talked about peptides are Semaglutide, Tirzepatide and Retatrutide . Of the three peptides, Semalutide is the most widely used weight loss peptide, while Retatrutide is the latest. Today, let's compare these three peptides.
Semaglutide Tirzepatide Retatrutide mode of action
Semaglutide is a GLP-1 receptor agonist;
Tirzepatide is a double receptor agonist of GIP and GLP-1.
Retatrutide is a triple receptor agonist for GIP, GLP-1 and GCG.
Only from the perspective of the mode of action of Semaglutide Tirzepatide Retatrutide , Semaglutide is more simple and Retatrutide is more extensive. So, is Retatrutide better?
Whether Retatrutide is better or not depends on where you evaluate it. If you look at weight loss alone, it is really the best. Here are their weight loss stats.
Semaglutide Tirzepatide Retatrutide weight loss data
The average weight loss after 68 weeks of Semaglutide was about 15 percent (34 pounds);
The average weight loss after 72 weeks of Tirzepatide was about 22.5% (52 pounds).
The average weight loss of Retatrutide after 48 weeks of use was about 24.2 percent (57.8 pounds).
Only from the experimental data, Retatrutide has a better weight loss effect, among which, the weight loss data of Tirzepatide is close to Retatrutide , but it is important to note that Tirzepatide is used after 72 weeks, while Retatrutide is used after 48 weeks. So, obviously, Retatrutide loses more weight and loses weight faster.
So, when Semaglutide Tirzepatide Retatrutide is compared together, is Retatrutide directly chosen?
Semaglutide Tirzepatide Retatrutide Approval
In fact, more people lose weight using Semaglutide than Retatrutide . It has to do with whether it gets FDA approval or not.
Semaglutide was first approved by the FDA for the treatment of type 2 diabetes in 2017, and then officially approved by the FDA for weight loss in 2021.
Tirzepatide received FDA approval for the treatment of type 2 diabetes in 2022, followed by clinical trials for weight loss, still awaiting FDA Approval for weight loss.
Retatrutide , which is directly focused on weight loss, is not being developed to treat type 2 diabetes as a priority, but rather to treat type 2 diabetes and lose weight in several trials simultaneously. The developers' confidence in Retatrutide can also be seen here.
Semaglutide Tirzepatide Retatrutide review
By comparing the three peptides Semaglutide Tirzepatide Retatrutide , we can see that Retatrutide is one of the peptides that loses weight faster and more weight, but it is still waiting for FDA approval. Semaglutide and Tirzepatide are currently used by more people, and if these two peptides can help you lose weight effectively and sustainably, congratulations. Depending on your physique and tolerance, if you use these two weight ...

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