Compared with the different action modes of Sermorelin acetate and HGH, the action modes of Sermorelin acetate and Tesamorelin could be said to be exactly the same. Sermorelin acetate and Tesamorelin are both analogues of growth hormone releasing hormone (GHRH), and both work by stimulating the synthesis of HGH(growth hormone). So how do I choose between these two peptides?
Different structure
The most direct difference between Sermorelin acetate and Tesamorelin is that both of them are derived from the structure of GHRH, in which Sermorelin acetate intercepted 29 amino acid sequences of GHRH and retained the ability of GHRH to stimulate HGH release. Tesamorelin has all 44 amino acid sequences of GHRH.
Different indication
peptides Sermorelin acetate and Tesamorelin acetate were studied and developed to treat corresponding diseases, among which Sermorelin acetate was mainly used to treat HGH deficiency in children and adults. Tesamorelin is primarily used to treat excess abdominal fat in HIV patients with lipodystrophy.
From their indications, it can be seen that Sermorelin acetate has a different emphasis than Tesamorelin, which provides guidance on how to choose them.
When to choose Tesamorelin?
Tesamorelin is mainly used to reduce excess abdominal fat accumulation, so you should choose Tesamorelin when your main purpose is fat loss. HGH has the effect of altering body composition (reducing fat, promoting lean muscle mass gain), and in cases where body fat mass is evident, the use of Tesamorelin helps to reduce fat quickly. However, Tesamorelin acts through HGH, and in addition to reducing fat, it also has the benefits of HGH, including improved metabolism and protein synthesis, increased lean muscle mass, faster healing, and improved athletic performance.
When do I choose Sermorelin acetate?
Sermorelin acetate is mainly used for HGH deficiency, therefore, the benefits of using Sermorelin acetate are the benefits of HGH, except that Sermorelin acetate increases the level of autocrine HGH and does not increase the level of endogenous HGH to a superphysiological level. When bodybuilders use Sermorelin acetate, the main effect is to improve lean muscle mass, that is, to increase muscle mass while avoiding fat accumulation.
Thus, Sermorelin acetate could be used when bodybuilders aim to increase metabolism and build muscle, or Tesamorelin acetate if they focus on fat reduction or cutting.